The Carolina Panthers (4-5) face the Arizona Cardinals (8-1) on the road Sunday in Week 10. Kickoff at State Farm Stadium is set for 4:05 p.m. ET. Below, we look at the Panthers vs. Cardinals odds and lines, and make our best NFL picks, predictions and bets.
CLICK HERE TO WATCH FREEThe Panthers have lost five of their last six games following a 3-0 start to the season. They have weathered injuries to RB Christian McCaffrey and now QB Sam Darnold, who suffered a fractured scapula and was placed on injured reserve. QB Cam Newton signed with the team this week but will not start this week as the team has opted to roll out QB P.J. Walker under center.
Arizona is the top seed in the NFC but is dealing with injuries of their own. QB Kyler Murray and WRs DeAndre Hopkins and A.J. Green were out in Week 9, but QB Colt McCoy led them to a 31-17 win over the San Francisco 49ers. They have the second-ranked scoring offense in the NFL (30.8 points per game) and the third-best scoring defense (17.2 points per game allowed).
Panthers at Cardinals odds, spread and lines
Odds provided by Tipico Sportsbook; access USA TODAY Sports’ betting odds for a full list. Lines last updated at 8:12 a.m. ET.
Money line: Panthers +330 (bet $100 to win $330) | Cardinals -450 (bet $450 to win $100)
Against the spread (ATS): Panthers +8.5 (-108) | Cardinals -8.5 (-112)
Over/Under (O/U): 43.5 (O: -105 | U: -115)
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Panthers at Cardinals key injuries
Panthers
DE Brian Burns (ankle) questionable
CB Rashaan Melvin (hand) out
QB Sam Darnold (shoulder) injured reserve
Cardinals
RB Chase Edmonds (ankle) out
OL Justin Pugh (calf) out
QB Kyler Murray (ankle) questionable
WR DeAndre Hopkins (hamstring) questionable
S Budda Baker (knee) questionable
WR Rondale Moore (neck) questionable
DE Jordan Phillips (groin) questionable
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Panthers at Cardinals odds, lines, predictions and picks
Prediction
Cardinals 30, Panthers 12
Money line
PASS on the money line. The Cardinals are going to take care of business and it isn’t worth the money to gain so little. Carolina allows the second-fewest yards per game in the league (293.1) but they do not have the offense to keep up with the Cardinals, especially with Walker at quarterback. They are turnover-prone and the Cardinals are one of the top defenses in the league in creating takeaways.
Against the spread
The Cardinals are 7-2 ATS this season, while the Panthers are 4-5 ATS and 2-2 ATS on the road.
Six of the Cardinals’ eight wins have been by at least 12 points. They have scored over 30 points seven times and allowed 20 or fewer seven times.
The only way the Panthers keep this game close is by not turning the ball over, creating multiple turnovers and using the run game to slow the game down. Short of all those things happening, the Cardinals are the way to go.
Take the CARDINALS -8.5 (-112).
Over/Under
Only two of the Panthers’ games this season have gone Over the projected total this season. Four of the Cardinals’ nine games have.
The Panthers have not cracked 20 points in their last three outings and in two of them, they scored 6 or fewer points. The Cardinals will get around the 30 points they have been scoring. The question is whether the Panthers can score more than 13 points against this Arizona defense.
Take UNDER 43.5 (-115).
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