What is Estee Derma Skin Serum? The solution to all of the problems a woman facing ageing is Estee Derma Skin Serum Benefits. When used by those with wrinkles and ageing skin, this product has produced impressive results. Its cutting-edge technology to rejuvenate, hydrate, and restore the more young, dazzling skin is one reason why this skincare solution has been deemed to be preferable to Botox in many aspects.