Bench to Bedside International Pain Conference 
There has been tremendous progress over the past decade in understanding the neurobiology of pain and CNS conditions. An explosion of cutting-edge methodologies and tools are emerging that more closely link preclinical and clinical development.

Bridging the gap from bench to bedside will require new and innovative ways of thinking, an increased investment in resources, and a collaborative approach among industry experts.

MD Biosciences research collaborative is bringing together some of the most innovative minds for a 2-day event. These experts will discuss how translational models, biomarkers and other clinically relevant endpoints, and interactions with clinical physicians will bring new approaches that aid in successful development of pain therapies.

Download PDF Brochure
Location
Beit Ha Pnay, Cultural Center
Moshe Levi St 6, Ness Ziona Israel
Date & Time
March 8, 2023
8:15 am - 5:00 pm
Evening social until 8:00 pm

March 9. 2023
7:15 am - 12:30 pm

Registration Fee: $200

Speakers
Dr Sigal Meilin
CSO, MD Biosciences Neuro
Peter Vestbjerg
Head of International Sales, Ellegaard Gottingen Minipigs
Andres Eskjær Jensen
Scientific team, Ellegaard Gottingen Minipigs
Dr Suzan Meijs
Assistant Professor, Faculty of Medicine, Aalborg University
Dr Hans Jürgen Solinski
Dept of Experimental Pain Research, Ruprecht-Karls- University
Dr Avital Schauder
Head of Histology, MD Biosciences Neuro
Dr Esther Pogatzki-Zahn
Department of Anesthesiology, University Hospital. Muenster
Dr Mikhail Kalinichev
Head of Translational Science, Addex Therapeutics
Dr Mark A. Mahann
Associate Professor Department of Neurosurgery, University of Utah
Dr Amir Arami
Head of the Hand surgery and Microsurgery department at Sheba Medical Center
Prof Shimon Rochkind
Associated Professor, Tel Aviv University, Head Microsurgery Assuta Medical Center
David Castel, DVM
Chief Veterinarian Officer, MD Biosciences Neuro
Dr Laurent Chesnel
VP Research and Development, Adiso Therapeutics
Dr Peter M Grace
Associate Professor, Dept of Symptom Research Laboratories of Neuroimmunology, MD Anderson Cancer Center
Dr Yoav Shulman
Neurophysiology, MD Biosciences Neuro
Dr. Daniel Segelcke
Department of Anesthesiology, University Hospital. Muenster
Join us for the International Pain Conference
Register by February 24, 2023.
Conference Program
Download PDF of full program here.
March 8, 2023
8:15 AM -  Registration
8:00 - 10:00 AM
Opening Session
WELCOME AND MDB NEURO OVERVIEW
Sigal Meilin PhD | CSO, MD Biosciences. Israel

THE HISTORY OF GÖTTINGEN MINIPIGS
Peter Vestbjerg | Head of International Sales, Ellegaard Gottingen Minipigs. Denmark

THE USE OF GÖTTINGEN MINIPIGS IN BIOMEDICAL RESEARCH
Andres Eskjær Jensen | Scientific team, Ellegaard Gottingen Minipigs. Denmark
10:00 AM coffee break
10:45 AM - 12:15 pm
Session I: THE USE OF PIGS IN PAIN RESEARCH: FOCUS ON CHRONIC PAIN
Chair: Dr Sigal Meilin, CSO MD Biosciences
THE ROLE OF PORCINE MODELS IN TRANSLATIONAL PAIN RESEARCH, WITH A FOCUS ON NEUROPATHIC MODELS
Suzan Meijs, PhD | Assistant Professor, Center for Neuroplasticity and Pain (CNAP), Dept. Of Health Science and Technology, The Faculty of Medicine, Aalborg University. Denmark

ELECTROPHYSIOLOGICAL AND TRANSCRIPTIONAL DISSECTION OF PIG SOMATOSENSORY NEURONS
Hans Jürgen Solinski, PhD | Department of Experimental Pain Research Mannheim Center for Translational Neuroscience, Ruprecht-Karls- University. Heidelberg, Germany

PNT MODEL FOR NEUROPATHIC PAIN IN THE PIGS AND SKIN BIOMARKERS
Avital Schauder, PhD | Head of Histology laboratory, MD Biosciences. Israel
12:15 pm lunch
1:15 - 2:45 pm
Session II: POST-SURGICAL PAIN-TRANSLATIONAL RESEARCH
Chair: Prof. Esther Pogatzki-Zahns
ADVANCES IN TRANSLATIONAL PAIN RESEARCH RELATED TO ACUTE AND CHRONIC PAIN AFTER SURGERY: PARALLEL EXPERIMENTS IN SPECIFIC RODENT PAIN MODELS, HUMANS AND PATIENTS
Esther Pogatzki-Zahn and Dr Dr. Daniel Segelcke, Univ. Prof. Dr. Med. | Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital. Muenster, Germany

THE ANALGESIC ACTIVITY OF ABOBOTULINUMTOXIN A IN POSTOPERATIVE PAIN MODELS IN THE PIG
Mikhail Kalinichev, PhD | Head of Translational Science, Addex Therapeutics. Switzerland

THE HTX-001 STORY
Sigal Meilin, PhD | CSO, MD Biosciences. Israel
2:45 pm coffee break
3:30 - 5:00 pm
Session III: PAINFUL NEUROMA CLINICAL AND PRECLINICAL ASPECTS
Chair: Prof. Shimon Rochind
NEUROMAS PATHOPHYSIOLOGIA NERVE REGENERATION AND ANIMAL MODELS
Mark A. Mahan, MD, FAANS | Associate Professor Department of Neurosurgery, University of Utah. USA

PAINFUL NEUROMA FROM THE CLINIC TO THE ANIMALS, TRYING TO ANSWER A CLINICAL QUESTION USING AN ANIMAL MODEL
Amir Arami, MD | Head of the Hand surgery and Microsurgery department at Sheba Medical Center. Israel

REVIVING MATRIX FOR RECONSTRUCTION OF TRAUMATIC INJURIES TO THE PERIPHERAL NERVES AND SPINAL CORD
Shimon Rochkind Director, Prof. Dr. MD/PhD | Peripheral Nerve Reconstruction division of the Department of Neurosurgery, Tel Aviv University, Senior Neurosurgeon and Specialist in Neurosurgery & Microsurgery, Tel Aviv Sourasky Medical Center. Israel
5:00 - 8:00 pm Social event and dinner
March 9, 2023
7:15 am meet for bus transport
8:30 - 9:00 am
CNS RESEARCH FACILITY TOUR
David (Didi) Castel, DVM | Chief Veterinarian Officer, MD Biosciences
Avital Schauder, PhD | Head of Histopathology Department, MD Biosciences
Sigal Meilin, PhD | CSO, MD Biosciences
9:00 am COFFEE BREAK
9:45 - 10:45 AM
Session IV: RESOLVING PAIN - DIFFERENT APPROACH TO PAIN THERAPY
Chair: Matan Nachliely PhD, MD Biosciences
ADS012, A NOVEL NON-COLONIZING ORALLY DELIVERED SINGLE STRAIN LIVE BIOTHERAPEUTIC PRODUCT (SS-LBP) FOR THE TREATMENT OF NEUROINFLAMMATORY DISEASES
Laurent Chesnel, PhD | VP Research and Development, AdisoTherapeutics. USA

EXERCISE PREHABILITATION AND IMMUNE REGULATION IN NEUROPATHIC PAIN
Peter M Grace, PhD | Associate Professor and Chair ad interim, Department of Symptom Research Laboratories of Neuroimmunology, MD Anderson Cancer Center. Houston, TX, USA
10:45 am coffee break
11:15 am - 12:15 pm
Session V: VIEW ON PAIN BIOMARKERS
Chair: Avital Schauder, MD Biosciences Israel
IN VIVO ELECTROPHYSIOLOGY A BIOMARKER FOR PAIN
Yoav Shulman, PhD | Neurophysiology, MD Biosciences. Israel

GABAPENTIN TREATMENT ATTENUATES INFLAMMATORY MARKERS IN STZ INDUCED NEUROPATHIC PAIN
Sigal Meilin, PhD | CSO, MD Biosciences. Israel

CLOSING REMARKS
Boxed lunch available to go
Location: Israel

 In the heart of the beautiful Mediterranean, Israel has a thriving life science and MedTech sector. Compared with the rest of the world, Israel spends the highest percentage of GDP on research and development. Make it a long weekend and enjoy a sunny start to spring with temperatures in the high 60s, low 70s in early March.
                                                       
Travel and Lodging
Conference Center
Beit Ha Pnay, Cultural Center                        
There is a free parking in front of the cultural center. The conference center is located at Moshe Levi St 6, Ness Ziona,  which is 4 km (2.5 miles) from the Hotel.

A bus to the conference center will wait in front of the hotel at 7:45 am for the hotel guests and participants that are arriving by train. At the end of the day (approx. 20:00) a bus will return the participants to the hotel/train station.
Hotel
Leonardo Boutique Rehovot Hotel
We have arranged a special rate at the Leonardo Boutique. Room rates for the conference are 580 NIS (single) or 660 NIS (double). In order to receive the conference rate, rooms must be booked by February 8, 2023. To reserve a conference room, please email [email protected] with the following details:
One night, March 08 Leonardo Boutique Rehovot Hotel
Order number: 116031. 


   
Local Transporation
Rehovot Ehud Hadar Train Station
The Leonardo Boutique is just a few steps from Rehovot Ehud Hadar Train Station.

A bus to the conference center will wait in front of the hotel at 7:45 am for the hotel guests and participants that are arriving by train. At the end of the day (approx. 20:00) a bus will return the participants to the hotel/train station.
                                                       
Air Travel
Ben Gurion Airport
International flights arrive at Ben Gurion International airport, which is approximately a 30 minute drive to the hotel.


                                                       
Contact Us
Questions about the Bench to Bedside International Pain Conference? Please use the form to send your message or question and we will be sure to get back to you as soon as possible. 
You can also contact MD Biosciences research collaborative by email or phone:

Phone (North America): (617) 764 6555
Phone (International): +972 (08) 939 6884

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