The RPG initiative is a collaboration between Ellegaard Göttingen Minipigs, Novo Nordisk, the Swedish University of Agricultural Sciences, and MD Biosciences.
Scientific Committee: Susi Søgaard, Cathrine Juel Bundgaard, Anneli Rydén, David (Didi) Castel, Orna Hifi and Sigal Meilin
Scientific Committee: Susi Søgaard, Cathrine Juel Bundgaard, Anneli Rydén, David (Didi) Castel, Orna Hifi and Sigal Meilin
Overview
Mission
Animal research involves painful procedures to varying degrees, yet little is known or shared about pain and anesthesia in pigs. The mission of this group is to address this issue by increasing shared knowledge on pain and anesthesia in pigs. We envision a space where members of the community can ask questions and share their knowledge.
Goals
• To create a community of people who work with pigs and who are interested in pain management and research, including animal caretakers, research assistants, veterinary nurses, animal technicians, veterinarians, students, and PhD researchers.
• To improve animal welfare according to the 5 Rs (Reduction, Replacement, Refinement, Responsibility, and Relevance).
• To highlight this subject by providing free access to scientific materials as well as to human experiences.
• To standardize the evaluation and management of pain scoring.
• To improve animal welfare according to the 5 Rs (Reduction, Replacement, Refinement, Responsibility, and Relevance).
• To highlight this subject by providing free access to scientific materials as well as to human experiences.
• To standardize the evaluation and management of pain scoring.
Webinars
Topic: The story of the post-operative translational model
Speaker: Sigal Meilin
On-demand: Click here to watch
Topic: The translational outcome measures: what do we measure in humans/animals, how do we ensure that these measures are translatable, where are we, where do we need to go?
Speaker: Suzan Meijs
On-demand: Clicker here to watch
Topic: Training minipigs in research settings: practical insights and strategies.
Speakers: Gil Doron, Cathrine Juel Bundegaard, Manuela Teti
On-demand: Clicker here to watch
Speaker: Sigal Meilin
On-demand: Click here to watch
Topic: The translational outcome measures: what do we measure in humans/animals, how do we ensure that these measures are translatable, where are we, where do we need to go?
Speaker: Suzan Meijs
On-demand: Clicker here to watch
Topic: Training minipigs in research settings: practical insights and strategies.
Speakers: Gil Doron, Cathrine Juel Bundegaard, Manuela Teti
On-demand: Clicker here to watch
Topics Addressed
• Which drug to use? What is the dose? What is the route of administration? What is the treatment regimen? What are the side effects of each drug?
• Is there an additional method besides drug therapy?
• Sometimes we encounter situations with controversial results: one lab suggests that a particular treatment works, while another lab believes that the same treatment does not work. This open discussion aims to better understand the source of discrepancies.
• PK-PD questions
• Each lab uses specific pain scoring systems. A unified pain scoring system may help us better understand the different results from various labs.
• Pain models in pigs: Given that pigs mimic the human peripheral nervous system and skin, it is important to further develop animal models with better translational relevance to humans.
• Sharing experiences regarding analgesia/anesthesia and its effects in different types of studies and discussing alternative types of anesthesia/analgesia that can be used when results might be affected by the drugs.
• Training in various procedures can help minimize the use of anesthesia and, at times, analgesia as well.
• Is there an additional method besides drug therapy?
• Sometimes we encounter situations with controversial results: one lab suggests that a particular treatment works, while another lab believes that the same treatment does not work. This open discussion aims to better understand the source of discrepancies.
• PK-PD questions
• Each lab uses specific pain scoring systems. A unified pain scoring system may help us better understand the different results from various labs.
• Pain models in pigs: Given that pigs mimic the human peripheral nervous system and skin, it is important to further develop animal models with better translational relevance to humans.
• Sharing experiences regarding analgesia/anesthesia and its effects in different types of studies and discussing alternative types of anesthesia/analgesia that can be used when results might be affected by the drugs.
• Training in various procedures can help minimize the use of anesthesia and, at times, analgesia as well.