16th ENII EFIS EJI Summer School on Advanced Immunology
Event Video 2023
Thank you to the 155 participants and 16 guest faculty members for having taken the time to spend a week together in beautiful Sardinia for the 16th edition of the ENII EFIS EJI Summer School on Advanced Immunology. We hope that the memories and friendships forged during this week stay with you for years to come!
16th ENII EFIS EJI Summer School on Advanced Immunology
Location
Hotel Carlos V, Alghero
Date & Time
May 12, 2023, 6:00 PM - May 19, 2023 - 1:00 PM
This 16th Summer School welcomes 16 internationally recognised faculty members and 155 PhD students and post docs from across Europe and beyond.
The scientific program features 16 guest faculty lessons, 22 short oral presentations from participants and 130 poster presentations over 5 days. A day of cultural excursions completes the week.
2023 Scientific Organisers:
Andreas Radbruch & Bernard Malissen
The scientific program features 16 guest faculty lessons, 22 short oral presentations from participants and 130 poster presentations over 5 days. A day of cultural excursions completes the week.
2023 Scientific Organisers:
Andreas Radbruch & Bernard Malissen
Guest Faculty
Institute for Regeneration and Repair & Centre for Inflammation Research, University of Edinburgh
Mucosal immunity and inflammation
Institute of Experimental Immunology, University of Zurich
Neuro-immune interactions
Max Planck Institute of Immunobiology and Epigenetics
Evolutionary novelties in vertebrate immune systems
Department of Imunology, Institut Pasteur, INSERM
Decoding immune responses to cancer and infection using intravital imaging
Department of Imunology, Institut Pasteur, INSERM
Innate lymphoid cells: development, differentiation and dynamics
VIB Center for Inflammation Research, Ghent University
Integration of macrophages within their tissue of residence
CIML Immunology
Unveiling the molecular basis of T cell malfunctions and disorders using multi-omics approaches
Human Genetics of Infectious Diseases, INSERM; Institut Imagine, Université de Paris
Human host factors in susceptibility to critical COVID-19 pneumonia
Deutsches Rheuma-Forschungszentrum Berlin
The switch from immune reaction to immunological memory
Institute of Biology III, Albert-Ludwigs-Universität Freiburg
The B cell receptor in quiescence and activation
Deutsches Rheuma-Forschungszentrum Berlin & Charité - Universitätsmedizin Berlin
Innate Memory
Institute of Microbiology, ETH Zürich & Institute for Research in Biomedicine, Università della Svizzera italiana
T cell heterogeneity
Institute of Experimental Immunology, University of Zurich
Interactions between cancer and the immune system: Multi-faceted action of cGAMP in the tumor microenvironment
Guest Faculty presence at the School
Partners
EFIS and the European Journal of Immunology are co-sponsors of the 2023 Summer School and have made travel bursaries available for eligible participants.
Schedule at a glance
Program
Friday, May 12 - Arrival
Registration (18:00-20:00, 21:00-22:00)
Dinner (20:00-21:30)
Saturday, May 13
Welcome Remarks (08:30)
Lecture (08:40-09:40): Thomas Boehm Evolutionary novelties in vertebrate immune systems
EFIS EJI Keynote Lecture (09:40-10:40): Anne Puel Human host factors in susceptibility to critical COVID-19 pneumonia
Coffee Break (10:40-11:10):
Lecture (11:10-12:10): Rino Rappuoli Vaccines 2050
Lecture (12:10-13:10): Chiara Romagnani Innate Memory
Lunch (13:15-14:15)
Participant short presentations: (16:15-17:15)
Coffee Break (17:15-17:35)
Tutorial Sessions: 17:45-19:05
Dinner (19:45-21:00)
Poster Session A (21:00-22:30)
Sunday, May 14
Lecture (09:00-10:00): Maries van den Broek Interactions between cancer and the immune system: Multi-faceted action of cGAMP in the tumor microenvironment
Lecture (10:00-11:00): Veni Papayannopoulos The multifaceted neutrophil in infection and disease
Coffee Break (11:00-11:20)
Lecture (11:30-12:30): Burkhard Becher Neuro-immune interactions
Lunch (13:00-14:00)
Participant short presentations: (16:00-17:30)
Coffee Break (17:30-17:50)
Tutorial Sessions: 18:00-19:00
Dinner (19:45-21:00)
Poster Session B (21:00-22:30)
Monday, May 15
Lecture (09:00-10:00): Bernard Malissen Unveiling the molecular basis of T cell malfunctions and disorders using multi-omics approaches.
Lecture (10:00-11:00): Michael Reth The B cell receptor in quiescence and activation
Coffee Break (11:00-11:20)
Lecture (11:30-12:30): James Di Santo Innate lymphoid cells: development, differentiation and dynamics
Lunch (13:00-14:00)
Participant short presentations: (16:00-17:30)
Coffee Break (17:30-17:50)
Tutorial Sessions: 18:00-19:00
Dinner (19:45-21:00)
Poster Session C (21:00-22:30)
Tuesday, May 16
Lecture (09:00-10:00): Martin Guilliams Integration of macrophages within their tissue of residence
Lecture (10:00-11:00): Andreas Radbruch The switch from immune reaction to immunological memory
Coffee Break (11:00-11:20)
Lecture (11:30-12:30): Federica Sallusto T cell heterogeneity
Lunch (13:00-14:00)
Participant short presentations: (16:00-17:30)
Coffee Break (17:30-17:50)
Tutorial Sessions: 18:00-19:00
Dinner (19:45-21:00)
Poster Session D (21:00-22:30)
Wednesday, May 17
Lecture (09:00-10:00): Calum Bain Mucosal Macrophages: Differentiation, dynamics and dysfunction
Lecture (10:00-11:00): Hyun-Dong Chang Immune interaction of microbiota
Coffee Break (11:00-11:20)
Lecture (11:30-12:30): Philippe Bousso Decoding immune responses to cancer and infection using intravital imaging
Lunch (13:00-14:00)
Participant short presentations: (16:00-17:30)
Coffee Break (17:30-17:50)
Tutorial Sessions: 18:00-19:00
Dinner (19:45-21:00)
Poster Session E (21:00-22:30)
Thursday, May 18
Cultural Excursions (optional) (Sign-up and times to be confirmed on-site)
Morning:
08:30 Depart Hotel, walk to Alghero Marina (20/25 min), board the boat DELPHINUS
09:00-11:30 Boat Excursion from Alghero Marina to visit the Neptune’s Cave under the Capo Caccia promontory.
12:30-13:30 Lunch in the Hotel
Afternoon:
13:30-18:30
Excursion by bus to the inimitable La Pelosa beach in the Stintino area, north-west point of Sardinia.
13:30 Buses depart from Hotel
17:30 Buses depart from La Pelosa beach
20:00 Farewell Dinner
21:30-23:30 DJ in the poster room
Friday, May 19 – Departure
Registration (18:00-20:00, 21:00-22:00)
Dinner (20:00-21:30)
Saturday, May 13
Welcome Remarks (08:30)
Lecture (08:40-09:40): Thomas Boehm Evolutionary novelties in vertebrate immune systems
EFIS EJI Keynote Lecture (09:40-10:40): Anne Puel Human host factors in susceptibility to critical COVID-19 pneumonia
Coffee Break (10:40-11:10):
Lecture (11:10-12:10): Rino Rappuoli Vaccines 2050
Lecture (12:10-13:10): Chiara Romagnani Innate Memory
Lunch (13:15-14:15)
Participant short presentations: (16:15-17:15)
Coffee Break (17:15-17:35)
Tutorial Sessions: 17:45-19:05
Dinner (19:45-21:00)
Poster Session A (21:00-22:30)
Sunday, May 14
Lecture (09:00-10:00): Maries van den Broek Interactions between cancer and the immune system: Multi-faceted action of cGAMP in the tumor microenvironment
Lecture (10:00-11:00): Veni Papayannopoulos The multifaceted neutrophil in infection and disease
Coffee Break (11:00-11:20)
Lecture (11:30-12:30): Burkhard Becher Neuro-immune interactions
Lunch (13:00-14:00)
Participant short presentations: (16:00-17:30)
Coffee Break (17:30-17:50)
Tutorial Sessions: 18:00-19:00
Dinner (19:45-21:00)
Poster Session B (21:00-22:30)
Monday, May 15
Lecture (09:00-10:00): Bernard Malissen Unveiling the molecular basis of T cell malfunctions and disorders using multi-omics approaches.
Lecture (10:00-11:00): Michael Reth The B cell receptor in quiescence and activation
Coffee Break (11:00-11:20)
Lecture (11:30-12:30): James Di Santo Innate lymphoid cells: development, differentiation and dynamics
Lunch (13:00-14:00)
Participant short presentations: (16:00-17:30)
Coffee Break (17:30-17:50)
Tutorial Sessions: 18:00-19:00
Dinner (19:45-21:00)
Poster Session C (21:00-22:30)
Tuesday, May 16
Lecture (09:00-10:00): Martin Guilliams Integration of macrophages within their tissue of residence
Lecture (10:00-11:00): Andreas Radbruch The switch from immune reaction to immunological memory
Coffee Break (11:00-11:20)
Lecture (11:30-12:30): Federica Sallusto T cell heterogeneity
Lunch (13:00-14:00)
Participant short presentations: (16:00-17:30)
Coffee Break (17:30-17:50)
Tutorial Sessions: 18:00-19:00
Dinner (19:45-21:00)
Poster Session D (21:00-22:30)
Wednesday, May 17
Lecture (09:00-10:00): Calum Bain Mucosal Macrophages: Differentiation, dynamics and dysfunction
Lecture (10:00-11:00): Hyun-Dong Chang Immune interaction of microbiota
Coffee Break (11:00-11:20)
Lecture (11:30-12:30): Philippe Bousso Decoding immune responses to cancer and infection using intravital imaging
Lunch (13:00-14:00)
Participant short presentations: (16:00-17:30)
Coffee Break (17:30-17:50)
Tutorial Sessions: 18:00-19:00
Dinner (19:45-21:00)
Poster Session E (21:00-22:30)
Thursday, May 18
Cultural Excursions (optional) (Sign-up and times to be confirmed on-site)
Morning:
08:30 Depart Hotel, walk to Alghero Marina (20/25 min), board the boat DELPHINUS
09:00-11:30 Boat Excursion from Alghero Marina to visit the Neptune’s Cave under the Capo Caccia promontory.
12:30-13:30 Lunch in the Hotel
Afternoon:
13:30-18:30
Excursion by bus to the inimitable La Pelosa beach in the Stintino area, north-west point of Sardinia.
13:30 Buses depart from Hotel
17:30 Buses depart from La Pelosa beach
20:00 Farewell Dinner
21:30-23:30 DJ in the poster room
Friday, May 19 – Departure
Short oral presentations
Saturday may 13
16:15
Filippo Bianchini, Istituto di Ricerca in Biomedicina (IRB), Bellinzona, Switzerland
HUMAN MONOCLONAL ANTIBODIES TO THE SPIKE SUBDOMAIN 1 NEUTRALIZE SARS-COV-2 AND ITS VARIANTS OF CONCERN (Abstract 6)
Douwe Bosma, Leiden University Medical Center, Leiden, Netherlands
CD4 T CELL HELP EXPANDS A MoDC POPULATION INVOLVED IN T CELL PRIMING (Abstract 8)
HUMAN MONOCLONAL ANTIBODIES TO THE SPIKE SUBDOMAIN 1 NEUTRALIZE SARS-COV-2 AND ITS VARIANTS OF CONCERN (Abstract 6)
Douwe Bosma, Leiden University Medical Center, Leiden, Netherlands
CD4 T CELL HELP EXPANDS A MoDC POPULATION INVOLVED IN T CELL PRIMING (Abstract 8)
sunday may 14
16:00
Gabrielle Chappell, Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK
TISSUE-RECRUITED INFLAMMATORY MACROPHAGES HAVE ENHANCED NLRP3 INFLAMMASOME PATHWAY ACTIVITY IN RHEUMATOID ARTHRITIS (Abstract 18)
Diana Coman, King's College London, London, UK
A FEEDBACK LOOP BETWEEN EPITHELIUM AND INNATE LYMPHOID CELLS CONTROLS INTESTINAL TGF-β1 DYNAMICS (Abstract 20)
Ana Raquel da Palma Coelho Pessoa da Silva, Champalimaud Foundation, Lisbon, Portugal
DENDRITIC CELLS, BRIDGING NEUROMODULATION AND IMMUNITY (Abstract 23)
Lyanne Derksen, UMC Utrecht, Utrecht, The Netherlands
HOW LONG DO LONG-LIVED PLASMA CELLS LIVE? (Abstract 27)
Sergio Gonzalez San Miguel, Max Planck Institute for Infection Biology, Berlin, Germany
DIFFERENTIATING HEMATOPOIETIC PROGENITOR STEM CELLS INTO NEUTROPHILS TO UNDERSTAND NUCLEAR LOBULATION (Abstract 39)
TISSUE-RECRUITED INFLAMMATORY MACROPHAGES HAVE ENHANCED NLRP3 INFLAMMASOME PATHWAY ACTIVITY IN RHEUMATOID ARTHRITIS (Abstract 18)
Diana Coman, King's College London, London, UK
A FEEDBACK LOOP BETWEEN EPITHELIUM AND INNATE LYMPHOID CELLS CONTROLS INTESTINAL TGF-β1 DYNAMICS (Abstract 20)
Ana Raquel da Palma Coelho Pessoa da Silva, Champalimaud Foundation, Lisbon, Portugal
DENDRITIC CELLS, BRIDGING NEUROMODULATION AND IMMUNITY (Abstract 23)
Lyanne Derksen, UMC Utrecht, Utrecht, The Netherlands
HOW LONG DO LONG-LIVED PLASMA CELLS LIVE? (Abstract 27)
Sergio Gonzalez San Miguel, Max Planck Institute for Infection Biology, Berlin, Germany
DIFFERENTIATING HEMATOPOIETIC PROGENITOR STEM CELLS INTO NEUTROPHILS TO UNDERSTAND NUCLEAR LOBULATION (Abstract 39)
monday may 15
16:00
Anna Heawood, University of Glasgow, Glasgow, UK
THE IMPACT OF HELICOBACTER HEPATICUS INFECTION ON HOST INNATE IMMUNITY (Abstract 41)
Lukas Heiberger, Deutsches Rheuma-Forschungszentrum, Berlin, Germany
MAINTENANCE OF TISSUE-RESIDENT MEMORY T LYMPHOCYTES BY STROMAL CELL-INDUCED PI3K SIGNALING (Abstract 42)
Kadam Pallavi, Ludwig Maximilians Universität Munich, Munich, Germany
DYNAMIC ADOPTION OF ANERGY BY ANTIGEN-EXHAUSTED CD4+ T CELLS (Abstract 47)
Sophia Helena Kasbrink, Heinrich-Heine University, Düsseldorf, Germany
MURINE GBP7 AND ITS INTERACTION WITH TOM1 AND T. GONDII SURFACE PROTEIN SRS29C IN PATHOGEN DEFENCE (Abstract 49)
Luka Krampert, Institut for Medical Microbiology and Hygiene Regensburg, Regensburg, Germany
ROLE OF INTRACELLULAR NA+ ACCUMULATION ON MACROPHAGE ACTIVATION AND FUNCTION (Abstract 53)
THE IMPACT OF HELICOBACTER HEPATICUS INFECTION ON HOST INNATE IMMUNITY (Abstract 41)
Lukas Heiberger, Deutsches Rheuma-Forschungszentrum, Berlin, Germany
MAINTENANCE OF TISSUE-RESIDENT MEMORY T LYMPHOCYTES BY STROMAL CELL-INDUCED PI3K SIGNALING (Abstract 42)
Kadam Pallavi, Ludwig Maximilians Universität Munich, Munich, Germany
DYNAMIC ADOPTION OF ANERGY BY ANTIGEN-EXHAUSTED CD4+ T CELLS (Abstract 47)
Sophia Helena Kasbrink, Heinrich-Heine University, Düsseldorf, Germany
MURINE GBP7 AND ITS INTERACTION WITH TOM1 AND T. GONDII SURFACE PROTEIN SRS29C IN PATHOGEN DEFENCE (Abstract 49)
Luka Krampert, Institut for Medical Microbiology and Hygiene Regensburg, Regensburg, Germany
ROLE OF INTRACELLULAR NA+ ACCUMULATION ON MACROPHAGE ACTIVATION AND FUNCTION (Abstract 53)
tuesday may 16
16:00
Xinyue Li, Kennedy Institute of Rheumatology, Oxford, UK
ELUCIDATING THE ROLE OF HELICOBACTER HEPATICUS EXOPOLYSACCHARIDES IN INFLAMMATORY DISEASES (Abstract 62)
Elham Sadat Mirfazeli, Amsterdam UMC, Amsterdam, Netherlands
ACTIVATED PHOSPHOINOSITIDE 3-KINASE δ (PI3Kδ) IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) (Abstract 72)
Andrew Morrison, Amsterdam UMC, Amsterdam, Netherlands
GENERATION OF 3D HUMAN LYMPH NODE ORGANOIDS TO STUDY IMMUNE RESPONSES IN MULTI-ORGAN-ON-CHIP MODELS (Abstract 74)
Bianca Partini, Università Vita-Salute San Raffaele, Milan, Italy
A TUMOR SIZE-DEPENDENT NEO-ANGIOGENIC SWITCH DETERMINES THE CAPACITY OF CD8+ T CELLS TO EXERT CANCER IMMUNE SURVEILLANCE WITHIN THE LIVER (Abstract 80)
Mathilde Ruggiu, Institut Pasteur, Paris, France
ANTI-PD-1 PROMOTES CD8 T CELL RESPONSES IN TUMOR-DRAINING LYMPH NODES BY INDUCING FOLLICULAR HELPER T CELL-DEPENDENT IL-4 RELEASE (Abstract 91)
ELUCIDATING THE ROLE OF HELICOBACTER HEPATICUS EXOPOLYSACCHARIDES IN INFLAMMATORY DISEASES (Abstract 62)
Elham Sadat Mirfazeli, Amsterdam UMC, Amsterdam, Netherlands
ACTIVATED PHOSPHOINOSITIDE 3-KINASE δ (PI3Kδ) IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) (Abstract 72)
Andrew Morrison, Amsterdam UMC, Amsterdam, Netherlands
GENERATION OF 3D HUMAN LYMPH NODE ORGANOIDS TO STUDY IMMUNE RESPONSES IN MULTI-ORGAN-ON-CHIP MODELS (Abstract 74)
Bianca Partini, Università Vita-Salute San Raffaele, Milan, Italy
A TUMOR SIZE-DEPENDENT NEO-ANGIOGENIC SWITCH DETERMINES THE CAPACITY OF CD8+ T CELLS TO EXERT CANCER IMMUNE SURVEILLANCE WITHIN THE LIVER (Abstract 80)
Mathilde Ruggiu, Institut Pasteur, Paris, France
ANTI-PD-1 PROMOTES CD8 T CELL RESPONSES IN TUMOR-DRAINING LYMPH NODES BY INDUCING FOLLICULAR HELPER T CELL-DEPENDENT IL-4 RELEASE (Abstract 91)
wednesday may 17
16:00
Marina Schernthanner, The Rockefeller University, New York, USA
LYMPHATICS ACT AS A SIGNALING HUB TO REGULATE INTESTINAL STEM CELL ACTIVITY (Abstract 97)
Hagen Sülzen, Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czechia
A TRYPANOSOMA BRUCEI GAMBIENSE SURFACE RECEPTOR FOR HUMAN COMPLEMENT C3 AND C3B AND IT’S ROLE IN THE RESTRICTION OF THE ALTNERATIVE PATHWAY (Abstract 114)
Luca Tiraboschi, IRCCS HUMANITAS Research Hospital, Rozzano, Italy
IMPACT OF INTRATUMORAL MICROBIOTA IN SOFT TISSUE SARCOMA TREATMENT EFFICACY (Abstract 117)
Etienne Villain, Institut Pasteur, Paris, France
COMPARISON OF IMMUNE VARIABILITY BETWEEN HEALTHY AFRICAN AND EUROPEAN ADULTS REVEALS BROAD SIMILARITIES AND SPECIFIC DIFFERENCES (Abstract 128)
Léa Zinsli, ETH Zürich, Zurich, Switzerland
DEIMMUNIZATION OF PEPTIDOGLYCAN HYDROLASES FOR THERAPEUTIC TREATMENT OF SYSTEMIC S. AUREUS INFECTIONS (Abstract 135)
LYMPHATICS ACT AS A SIGNALING HUB TO REGULATE INTESTINAL STEM CELL ACTIVITY (Abstract 97)
Hagen Sülzen, Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Prague, Czechia
A TRYPANOSOMA BRUCEI GAMBIENSE SURFACE RECEPTOR FOR HUMAN COMPLEMENT C3 AND C3B AND IT’S ROLE IN THE RESTRICTION OF THE ALTNERATIVE PATHWAY (Abstract 114)
Luca Tiraboschi, IRCCS HUMANITAS Research Hospital, Rozzano, Italy
IMPACT OF INTRATUMORAL MICROBIOTA IN SOFT TISSUE SARCOMA TREATMENT EFFICACY (Abstract 117)
Etienne Villain, Institut Pasteur, Paris, France
COMPARISON OF IMMUNE VARIABILITY BETWEEN HEALTHY AFRICAN AND EUROPEAN ADULTS REVEALS BROAD SIMILARITIES AND SPECIFIC DIFFERENCES (Abstract 128)
Léa Zinsli, ETH Zürich, Zurich, Switzerland
DEIMMUNIZATION OF PEPTIDOGLYCAN HYDROLASES FOR THERAPEUTIC TREATMENT OF SYSTEMIC S. AUREUS INFECTIONS (Abstract 135)
About the Participants
155 PhD students (26% 1Y, 33% 2Y, 30% 3&4Y) and post docs/other (10%) from across Europe (and beyond) form the largest Summer School class to date.
(last names B-D are relocated to the end due to a glitch, apologies)
(last names B-D are relocated to the end due to a glitch, apologies)
Conference Location
Hotel Carols V, Alghero, Sardinia
Alghero is a beautiful beach town on the northwest coast of Sardinia that is filled with historical charm. Settled since prehistoric times, the area has been controlled by numerous different European powers, each leaving its own distinctive marks. These range from the Bronze Age towers to 16th-century city walls, with other highlights including the town’s cathedral and historic churches.
Alghero is a beautiful beach town on the northwest coast of Sardinia that is filled with historical charm. Settled since prehistoric times, the area has been controlled by numerous different European powers, each leaving its own distinctive marks. These range from the Bronze Age towers to 16th-century city walls, with other highlights including the town’s cathedral and historic churches.
Local recommendations
Gelateria Igloo
Artisanal gelato and granita from fresh fruit on the Alghero sea wall.
Artisanal gelato and granita from fresh fruit on the Alghero sea wall.
La Bottega di Tommy
Small but well stocked specialty food shop in the historic center selling sardinian wine, cheese, cured meats. Shipping available.
Small but well stocked specialty food shop in the historic center selling sardinian wine, cheese, cured meats. Shipping available.
Ichnos Sardinian Artisan Products
Offering a curated selection of jewelry, knives, textiles and ceramics.
A preview on their website.
Across the road from Tommy's
Offering a curated selection of jewelry, knives, textiles and ceramics.
A preview on their website.
Across the road from Tommy's